Article
Oxidative and amphotericin B-mediated cell death in the opportunistic pathogen Aspergillus fumigatus is associated with an apoptotic-like phenotype.
Microbiology (Reading, England) - 1 Jun 2004
Mousavi S Amin A, Robson Geoffrey D
Abstract excerpt
When protoplasts of the opportunistic fungal pathogen Aspergillus fumigatus were treated with low but toxic levels of hydrogen peroxide (0.1 mM) or amphotericin B (0.5 microg ml(-1)), loss of cell viability and death were associated with a number of phenotypic changes characteristic of apoptosis. The percentage of protoplasts staining positive with annexin V-FITC, an indicator of the externalization of...
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