Article
Linkage analysis of smoking initiation and quantity in Dutch sibling pairs.
The pharmacogenomics journal - 1 Jan 2004
Vink J M, Beem A L, Posthuma D, Neale M C, Willemsen G, Kendler K S, Slagboom P E, Boomsma D I
Abstract excerpt
The heritability of smoking initiation (SI) and number of cigarettes smoked (NC) was determined in 3657 Dutch twin pairs. For SI a heritability of 36% was found and for NC of 51%. Both SI and NC were also significantly influenced by environmental factors shared by family members. The etiological factors that influence these traits partly overlap. Linkage analyses were performed on data of 536 DZ twins and...
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