Article
Determination of amino acid pairs sensitive to variants in human copper-transporting ATPase 2.
Biochemical and biophysical research communications - 18 Jun 2004
Wu Guang, Yan Shaomin
Abstract excerpt
In this study, we use our probabilistic approach to analyze the amino acid pairs in human copper-transporting ATPase 2 (ATP7B) in order to determine which amino acid pairs are more sensitive to 125 variants from missense mutant human ATP7B. The results show 97.6% of 125 variants occur at randomly unpredictable amino acid pairs, which account for 80.9% of amino acid pairs in ATP7B, and the chance of occurring of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
