Article
Altered arterial homeostasis and cerebral aneurysms: a molecular epidemiology study.
Neurosurgery - 1 Jun 2004
Kassam Amin B, Horowitz Michael, Chang Yue-Fang, Peters David
Abstract excerpt
OBJECTIVE: We hypothesized that patients with intracranial cerebral aneurysms (IAs) harbor a molecular defect in the process responsible for maintaining arterial integrity (arterial homeostasis). In this study, we undertook a preliminary assessment of differential expression of key molecules involved with each phase of homeostasis: arterial flow modulation, arterial tear and repair, and the ensuing extracellular...
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