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Article

Gene expression profiles in human ruptured and unruptured intracranial aneurysms: what is the role of inflammation?

Stroke - 1 Feb 2010

Pera Joanna, Korostynski Michal, Krzyszkowski Tadeusz, Czopek Jacek, Slowik Agnieszka, Dziedzic Tomasz, Piechota Marcin, Stachura Krzysztof, Moskala Marek, Przewlocki Ryszard, Szczudlik Andrzej

Abstract excerpt

BACKGROUND AND PURPOSE: Mechanisms underlying development and rupture of intracranial aneurysms (IA) are poorly recognized. The majority of studies on human tissue have focused on predefined pathways. We sought to analyze global gene expression patterns of ruptured IA, unruptured IA, and control vessels. METHODS: Transcription profiles were studied in human ruptured (n=8) and unruptured (n=6) IA, as well as in...

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PMID: 20044533
DOI: 10.1161/STROKEAHA.109.562009

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Source receipt: pubmed, retrieved 7 Sept 2026.

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