Article
Association of schizophrenia and partial trisomy of chromosome 5p. A case report.
Schizophrenia research - 1 Jul 1992
Malaspina D, Warburton D, Amador X, Harris M, Kaufmann C A
Abstract excerpt
A normal balanced chromosome 5 translocation carrier (5:14) (p14.1; q32.3) produced one offspring with a 5p deletion syndrome (cri du chat syndrome) and two with a partial trisomy (one with schizophrenia and the other with refractory epilepsy). We had hypothesized that the translocation might be complex and involve 5q, overlapping with a schizophrenia associated area described by Bassett et al., (1988)....
Topics
- Adolescent
- Chromosomes, Human, Pair 5
- Female
- Humans
- Karyotyping
- Neuropsychological Tests
- Pedigree
- Phenotype
- Psychiatric Status Rating Scales
- Schizophrenia
- Schizophrenic Psychology