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Article

Determination of the rdw rat genotype by polymerase chain reaction with allele-specific primer (PCR-ASP).

Experimental animals - 1 Apr 2004

Masaki Tamotsu, Takamatsu Ken, Umezu Motoaki

Abstract excerpt

The rat carrying the rdw mutation (rdw rat) is a dwarf mutant with hypothyroidism that is caused by a single G to C transversion in the thyroglobulin gene. Therefore, the development of a simple method for molecular-based genotyping of this mutation has been problematic. We have developed a rapid and simple genotyping method that provides identification of both the rdw and wild-type allele. This polymerase chain...

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PMID: 15153679
DOI: 10.1538/expanim.53.155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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