Article
Refinement of a locus for Marie Unna hereditary hypotrichosis to a 1.1-cM interval at 8p21.3.
The British journal of dermatology - 1 May 2004
He P P, Zhang X J, Yang Q, Li M, Liang Y H, Yang S, Yan K L, Cui Y, Shen Y Y, Wang H Y, Sun L D, Du W H, Shen Y J, Xu S J, Huang W
Abstract excerpt
BACKGROUND: Marie Unna hereditary hypotrichosis (MUHH) is a rare autosomal congenital alopecia with progressive hair loss starting in early childhood and accelerating at puberty. A locus for MUHH has been mapped on chromosome 8p21 but no genes for MUHH have been identified to date. OBJECTIVES: To refine the MUHH locus to a narrow chromosome region to facilitate cloning of the gene. METHODS: We performed...
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