Article
Gene mining: a novel and powerful ensemble decision approach to hunting for disease genes using microarray expression profiling.
Nucleic acids research - 1 Jan 2004
Li Xia, Rao Shaoqi, Wang Yadong, Gong Binsheng
Abstract excerpt
Current applications of microarrays focus on precise classification or discovery of biological types, for example tumor versus normal phenotypes in cancer research. Several challenging scientific tasks in the post-genomic epoch, like hunting for the genes underlying complex diseases from genome-wide gene expression profiles and thereby building the corresponding gene networks, are largely overlooked because of...
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