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Article

Prednisone reduces muscle degeneration in dystrophin-deficient Caenorhabditis elegans.

Neuromuscular disorders : NMD - 1 Jun 2004

Gaud Aurélie, Simon Jean-Marc, Witzel Thomas, Carre-Pierrat Maité, Wermuth Camille G, Ségalat Laurent

Abstract excerpt

Duchenne muscular dystrophy is a degenerative muscular disease caused by mutations in the dystrophin gene. There is no curative treatment against Duchenne muscular dystrophy. In several countries, the steroid prednisone (or analogs) is prescribed as a palliative treatment. In the model animal Caenorhabditis elegans, mutations of the dys-1 dystrophin-like gene lead to a muscular degenerative phenotype when they...

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Source

Identifiers

PMID: 15145337
DOI: 10.1016/j.nmd.2004.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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