Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A metastasis of an adenocarcinoma in a BRCA1 mutation carrier, a diagnostic problem not solved by morphology alone.

Human pathology - 1 May 2004

Kuenen-Boumeester Vibeke, Den Bakker Michael, Dinjens Winand N m, Seynaeve Caroline

Abstract excerpt

To increase awareness of the possible coexistence of an ovarian and breast carcinoma in a BRCA1 mutation carrier, we describe a patient with primary ovarian cancer who developed distant metastases after 3 years and again after 6 years. Surprisingly, at that time an occult breast carcinoma was identified to be the origin of the 2 metastatic locations as confirmed by molecular analysis. Eventually the patient could...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Immunohistochemistry

Share to Lymphatic Metastasis

Share to Neoplasms, Second Primary

Share to Ovarian Neoplasms

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 15138940
DOI: 10.1016/j.humpath.2003.11.008

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A metastasis of an adenocarcinoma in a BRCA1 mutation carrier, a diagnostic problem not solved by morphology alone.PMID 15138940Read ↗

[Multiple primary malignancies in BRCA1 mutation carriers--two clinical cases].Semantic proximity Read ↗

A surveillance conundrum: a case of 4 distinct primary malignancies in a BRCA-1 mutation carrier.Semantic proximity Read ↗

The diagnosis of a metastatic breast tumor from ovarian cancer by the succession of a p53 mutation: a case report.Semantic proximity Read ↗

The unknown biology of the unknown primary tumour: a literature review.Semantic proximity Read ↗

Solitary brain metastasis in a patient with ovarian cancer with BRCA2 mutation.Semantic proximity Read ↗

A patient with a noninvasive mucinous ovarian borderline tumor presenting with late pleural metastases.Semantic proximity Read ↗

Synchronous ovarian dysgerminoma and breast carcinoma in a patient with positive immunostain of BRCA1.Semantic proximity Read ↗

A case of BRCA2-pathogenic variant breast cancer with metachronous endometrial cancer and pancreatic cancer: Case report and review of literatureSemantic proximity Read ↗

A case of multiple protruding and flat colorectal tumors analyzed by a cDNA array.Semantic proximity Read ↗

[Differential diagnosis of ovarian metastases].Semantic proximity Read ↗

A case of unknown primary melanoma detected with a BRAF gene mutation from a pleural fluid cell block.Semantic proximity Read ↗

Contralateral breast cancer: molecular differentiation between metastasis and second primary cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.