Article
Phenotype-specific treatment of difficult asthma in children.
Paediatric respiratory reviews - 1 Jun 2004
Payne Donald, Bush Andrew
Abstract excerpt
Most children with asthma can be treated successfully with low-to-moderate doses of inhaled corticosteroid and long-acting beta-2 agonist. Those that fail to respond are a heterogeneous group. We propose that the nature and type of any steroid-resistant inflammation, the extent of any persistent airflow limitation and the extent of bronchial hyper-reactivity should be determined separately to allow a rational...
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