Article
Overexpression of p27BBP in head and neck carcinomas and their lymph node metastases.
Head & neck - 1 May 2004
Rosso Paola, Cortesina Giorgio, Sanvito Francesca, Donadini Alessandra, Di Benedetto Barbara, Biffo Stefano, Marchisio Pier Carlo
Abstract excerpt
BACKGROUND: p27(BBP) is a regulator of ribosome assembly and an essential nuclear and cytoplasmic component of eukaryotes. METHODS: We investigated the immunochemical distribution of p27(BBP) in head and neck carcinomas, in the associated normal mucosa, and in regional lymph nodes. RESULTS: p27(BBP) is detectable in mucosal cells but is overexpressed in carcinomas, highly concentrated in large polymorphous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.