Article
Postmortem molecular screening in unexplained sudden death.
Journal of the American College of Cardiology - 5 May 2004
Chugh Sumeet S, Senashova Olga, Watts Allison, Tran Phuoc T, Zhou Zhengfeng, Gong Qiuming, Titus Jack L, Hayflick Susan J
Abstract excerpt
OBJECTIVES: We examined the prevalence of defects in arrhythmia-related candidate genes among patients with unexplained sudden cardiac death (SCD). BACKGROUND: Patients with unexplained sudden death may constitute up to 5% of overall SCD cases. For such patients, systematic postmortem genetic analysis of archived tissue, using a candidate gene approach, may identify etiologies of SCD. METHODS: We performed...
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