Article
Molecular autopsy of sudden unexplained deaths reveals genetic predispositions for cardiac diseases among young forensic cases.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 1 Nov 2017
Hellenthal Nicole, Gaertner-Rommel Anna, Klauke Bärbel, Paluszkiewicz Lech, Stuhr Markus, Kerner Thoralf, Farr Martin, Püschel Klaus, Milting Hendrik
Abstract excerpt
AIMS: Coronary artery disease accounts for the majority of sudden cardiac deaths (SCD) in the older population whereas cardiomyopathies and arrhythmogenic abnormalities predominate in younger SCD victims (<35 years) with a significant genetic component. The elucidation of the pathogenetic cause of death might be relevant for the prevention of further deaths within affected families. Aim of this study was to...
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