Article
Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage
22 Apr 2004
Abstract excerpt
BACKGROUND: Sperm DNA integrity is essential for the accurate transmission of genetic information. The clinical significance of this assessment lies in its association with not only natural conception rates, but also the success of assisted reproduction technology (ART). It has been reported that sperm chromatin structure assay (SCSA) identified thresholds for negative pregnancy outcome after ART when the DNA...
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