Article
Genetic isolates in Corsica (France): linkage disequilibrium extension analysis on the Xq13 region.
European journal of human genetics : EJHG - 1 Aug 2004
Latini Veronica, Sole Gabriella, Doratiotto Silvia, Poddie Daniela, Memmi Marc, Varesi Laurent, Vona Giuseppe, Cao Antonio, Ristaldi Maria Serafina
Abstract excerpt
Genetic isolates with a history of a small founder population, long-lasting isolation and population bottlenecks represent exceptional resources in the identification of genes involved in the pathogenesis of multifactorial diseases. In these populations, the disease allele reveals linkage disequilibrium (LD) with markers over significant genetic intervals, therefore facilitating disease locus identification. This...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
