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Article

No association of the Asp298 variant of the endothelial nitric oxide synthase gene with preeclampsia.

American journal of hypertension - 1 May 2004

Landau Ruth, Xie Hong-Guang, Dishy Victor, Wood Alastair J J, Stein C Michael, Smiley Richard M

Abstract excerpt

BACKGROUND: Preeclampsia, the most common serious complication of pregnancy, is characterized by vasoconstriction, dysfunction of the vascular endothelium, and hypertension. Unidentified genetic factors and impaired nitric oxide (NO)-mediated vasodilation are thought to contribute to the development of the syndrome. Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene affect NO production and have...

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Identifiers

PMID: 15110896
DOI: 10.1016/j.amjhyper.2004.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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