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Article

Cdc42 and the actin-related protein/neural Wiskott-Aldrich syndrome protein network mediate cellular invasion by Cryptosporidium parvum.

Infection and immunity - 1 May 2004

Chen Xian-Ming, Huang Bing Q, Splinter Patrick L, Orth James D, Billadeau Daniel D, McNiven Mark A, LaRusso Nicholas F

Abstract excerpt

Cryptosporidium parvum invasion of epithelial cells involves host cell membrane alterations which require a remodeling of the host cell actin cytoskeleton. In addition, an actin plaque, possibly associated with the dense-band region, forms within the host cytoplasm at the host-parasite interface. Here we show that Cdc42 and RhoA, but not Rac1, members of the Rho family of GTPases, are recruited to the...

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Source

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Identifiers

PMID: 15102814
DOI: 10.1128/IAI.72.5.3011-3021.2004
PMCID: PMC387898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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