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Article

Cell surface expression of the prion protein in yeast does not alter copper utilization phenotypes.

The Journal of biological chemistry - 9 Jul 2004

Li Aimin, Dong Jiaxin, Harris David A

Abstract excerpt

Prion diseases are fatal neurodegenerative disorders that result from conversion of a normal, cell surface glycoprotein (PrP(C)) into a conformationally altered isoform (PrP(Sc)) that is thought to be infectious. Although a great deal is known about the role of PrP(Sc) in the disease process, the physiological function of PrP(C) has remained enigmatic. In this report, we have used the yeast Saccharomyces...

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Identifiers

PMID: 15090539
DOI: 10.1074/jbc.M402517200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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