Article
Mutational analysis of RsbT, an activator of the Bacillus subtilis stress response transcription factor, sigmaB.
Journal of bacteriology - 1 May 2004
Woodbury Robyn L, Luo Tingqiu, Grant Lindsay, Haldenwang W G
Abstract excerpt
SigmaB, the stress-activated sigma factor of Bacillus subtilis, requires the RsbT protein as an essential positive regulator of its physical stress pathway. Stress triggers RsbT to both inactivate the principal negative regulator of the physical stress pathway (RsbS) by phosphorylation and activate a phosphatase (RsbU) required for sigmaB induction. Neither the regions of RsbT that are involved in responding to...
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