An unusual Ala12Thr polymorphism in the 1A alpha-helical segment of the companion layer-specific keratin K6hf: evidence for a risk factor in the etiology of the common hair disorder pseudofolliculitis barbae.

doi:10.1111/j.0022-202X.2004.22309.x

Article

An unusual Ala12Thr polymorphism in the 1A alpha-helical segment of the companion layer-specific keratin K6hf: evidence for a risk factor in the etiology of the common hair disorder pseudofolliculitis barbae.

The Journal of investigative dermatology - 1 Mar 2004

Winter Hermelita, Schissel Daniel, Parry David A D, Smith Thomasin A, Liovic Mirjana, Birgitte Lane E, Edler Lutz, Langbein Lutz, Jave-Suarez Luis F, Rogers Michael A, Wilde Joseph, Peters Gerald, Schweizer Jürgen

Abstract excerpt

Pseudofolliculitis barbae (PFB) is a common hair disorder characterized by a pustular foreign body inflammatory reaction that is induced by ingrown hairs of the facial and submental (barbea) regions after regular shaving. It occurs predominantly in black males, while it is rather rare and usually far less severe in Caucasian males. Black individuals have a higher propensity of developing PFB due to their genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Keratins

Share to Mutation

Share to Polymorphism, Genetic

Share to Protein Structure, Secondary

Share to Risk Factors

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

An unusual Ala12Thr polymorphism in the 1A alpha-helical segment of the companion layer-specific keratin K6hf: evidence for a risk factor in the etiology of the common hair disorder pseudofolliculitis barbae.PMID 15086549Read

Pseudofolliculitis cutis: a vexing disorder of hair growth.Semantic proximity Read

The twisting tale of woolly hair: a trait with many causes.Semantic proximity Read

Is the Loose Anagen Hair Syndrome a Keratin Disorder?Semantic proximity Read

A novel AAGAB mutation in a Peruvian family with punctate palmoplantar keratoderma.Semantic proximity Read

Aquagenic wrinkling of the palms in a cystic fibrosis carrier.Semantic proximity Read

No evidence for association of the TP53 12139 and the BAX-248 polymorphisms with endemic pemphigus foliaceus (fogo selvagem).Semantic proximity Read

A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair FollicleSemantic proximity Read

Inherited blistering skin diseases: underlying molecular mechanisms and emerging therapies.Semantic proximity Read