Cyanidin and Malvidin from<i> Oryza sativa</i> cv. Heugjinjubyeo Mediate Cytotoxicity against Human Monocytic Leukemia Cells by Arrest of G₂/M Phase and Induction of Apoptosis

Abstract excerpt

Oryza sativa cv. Heugjinjubyeo (Gramineae), anthocyanin-pigmented rice, having dark purple grains, is known broadly as enriched rice with an improved taste. Two bioactive compounds were isolated from the 0.5% HCl−ethyl alcohol soluble fraction of the aleurone layer of O. sativa cv. Heugjinjubyeo through an activity-monitored fractionation and isolation method. From spectral analysis, the cytotoxic components were...

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