Article
Attenuation of an avian pathogenic Escherichia coli strain due to a mutation in the rpsL gene.
Avian diseases - 1 Jan 2000
Amoako K K, Prysliak T, Potter A A, Collinson S K, Kay W W, Allan B J
Abstract excerpt
The diseases caused by pathogenic Escherichia coli constitute a major economic loss to the poultry industry. The development of a live oral E. coli vaccine to prevent or reduce diseases in poultry had been the objective of our work. Four spontaneous streptomycin-dependent (str-dependent) mutants were generated from a virulent avian strain that contains a mutation in the fur region of the chromosome. Genetic...
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