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Article

Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy.

Lancet (London, England) - 31 Jan 2004

Murphy Ross T, Mogensen Jens, Shaw Anthony, Kubo Toru, Hughes Sian, McKenna William J

Abstract excerpt

Idiopathic dilated cardiomyopathy is a common cause of heart failure. Half of cases are believed to be hereditary, and mutations in cardiac sarcomeric contractile protein genes have been reported with autosomal dominant inheritance. We used mutation analysis suitable for identification of both dominant and recessive mutations to investigate the sarcomeric gene for cardiac troponin I (TNNI3) in 235 patients with...

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Share to Amino Acid Substitution
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 15070570
DOI: 10.1016/S0140-6736(04)15468-8

Genes

TNNI3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy.PMID 15070570Read ↗

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