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HER-2/neu and p53 in Osteosarcoma: An Immunohistochemical and Fluorescence In Situ Hybridization Analysis

1 Jan 2004

Abstract excerpt

The overexpression of HER-2/neu and p53 has been associated with poor outcome in many neoplasms. Their role in patients with osteosarcoma is unclear. We studied the expression of HER-2/neu and p53 in 22 osteosarcoma samples (from 20 patients--2 had locally recurrent disease) biopsied at the University of Medicine and Dentistry of New Jersey (UMDNJ) from 1996-2000 using both immunohistochemical (IHC) and...

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PMID: 15069760
DOI: 10.1081/cnv-120027577

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