Article
MEPS parameters and graph analysis for the use of recombination to construct ordered sets of overlapping clones.
Genomics - 1 Aug 1992
Thaler D S, Noordewier M O
Abstract excerpt
Homologous recombination can provide a basis for the construction of an ordered set of overlapping clones. The principle is to make two libraries, each in a vector that has a different selectable marker flanking the insert site. Recombination between the flanking markers, leading to a selectable phenotype, can only occur as the consequence of crossing over between inserts. The two libraries are crossed in a...
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