Screening for mutations in BMP4 and FOXC1 genes in congenital anomalies of the kidney and urinary tract in humans.

Abstract excerpt

Recent studies have demonstrated in mice that bone morphogenetic protein 4 (BMP4) and forkhead transcription factor 1 (FOXC1) are involved in the organogenesis of the kidney and urinary tract and that derangement of either gene, BMP4 or FOXC1, leads to development of congenital anomalies of the k...

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