Article
The role of cysteine residues in tellurite resistance mediated by the TehAB determinant.
Biochemical and biophysical research communications - 22 Oct 2000
Dyllick-Brenzinger M, Liu M, Winstone T L, Taylor D E, Turner R J
Abstract excerpt
TehATehB is a tellurite (TeO(2-)(3)) resistance determinant found on the Escherichia coli chromosome. Normally silent, it specifies a minimal inhibitory concentration (MIC) of 2 microg K(2)TeO(3)/ml unless upregulated or present on a multicopy plasmid which results in an MIC of 128 microg/ml. Both TehA and TehB have three cysteine residues. Oligonucleotide site-directed mutagenesis was carried out to...
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