Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An enzyme immunoassay of ADAMTS13 distinguishes patients with thrombotic thrombocytopenic purpura from normal individuals and carriers of ADAMTS13 mutations.

Thrombosis and haemostasis - 1 Apr 2004

Zhou Wenhua, Tsai Han-Mou

Abstract excerpt

Recent studies demonstrate that assay of ADAMTS13, a circulating zinc metalloprotease that cleaves von Willebrand factor (VWF) at the Y1605-M1606 bond, is an important tool in the diagnosis of thrombotic thrombocytopenic purpura (TTP). In order to develop a method that could be adapted for genera...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADAM Proteins
Share to ADAMTS13 Protein
Share to Histidine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoenzyme Techniques

Share to Metalloendopeptidases

Share to Peptide Fragments

Share to Purpura, Thrombotic Thrombocytopenic

Share to von Willebrand Factor

Source

Identifiers

PMID: 15045144
DOI: 10.1160/TH03-11-0675

Genes

ADAMTS13
VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15045144-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An enzyme immunoassay of ADAMTS13 distinguishes patients with thrombotic thrombocytopenic purpura from normal individuals and carriers of ADAMTS13 mutations.PMID 15045144Read ↗

[Thrombotic Thrombocytopenic Purpura --Pathophysiology and Assays of ADAMTS13 Activity].Semantic proximity Read ↗

ADAMTS13 and TTP.Semantic proximity Read ↗

ADAMTS13 phenotype in plasma from normal individuals and patients with thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

ADAMTS13 testing update: Focus on laboratory aspects of difficult thrombotic thrombocytopenic purpura diagnoses and effects of new therapies.Semantic proximity Read ↗

Role of ADAMTS13 in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

Thrombotic thrombocytopenic purpura associated with von Willebrand factor-cleaving protease (ADAMTS13) deficiency in children.Semantic proximity Read ↗

Pharmacodynamic Profile of a Recombinant ADAMTS13 (BAX930) in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome (USS))Semantic proximity Read ↗

Molecular basis of ADAMTS13 dysfunction in thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

ADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies.Semantic proximity Read ↗

von Willebrand factor cleaving protease (ADAMTS-13) and ADAMTS-13 neutralizing autoantibodies in 100 patients with thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

ADAMTS13 activity and inhibitor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.