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Article

Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells.

The Journal of biological chemistry - 4 Jun 2004

Zhou Xiaoying, Murphy Frank R, Gehdu Nitu, Zhang Junlong, Iredale John P, Benyon R Christopher

Abstract excerpt

Hepatic stellate cells are the major source of the extracellular matrix that accumulates in fibrotic liver. During progressive liver fibrosis, hepatic stellate cells proliferate, but during resolution of fibrosis there is extensive stellate cell apoptosis that coincides with degradation of the li...

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PMID: 15044441
DOI: 10.1074/jbc.M311668200

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BAX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15044441-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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