Article
Cytogenetic and molecular analysis of a family with three brothers afflicted with germ-cell cancer.
Clinical genetics - 1 Jan 2004
Ottesen A M, Rajpert-De Meyts E, Holm M, Andersen I-L F, Vogt P H, Lundsteen C, Skakkebaek N E
Abstract excerpt
A thorough cytogenetic investigation and an analysis of detailed questionnaires were performed in a family with three brothers afflicted with germ-cell tumors (GCTs), in an attempt to detect a congenital factor related either to a hereditary genetic background or an environmental/lifestyle influence. One brother had an intracranial tumor in the pineal region and the two others had testicular tumors. Peripheral...
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