Article
Cost-effective analysis of candidate genes using htSNPs: a staged approach.
Genes and immunity - 1 Jun 2004
Lowe C E, Cooper J D, Chapman J M, Barratt B J, Twells R C J, Green E A, Savage D A, Guja C, Ionescu-Tîrgovişte C, Tuomilehto-Wolf E, Tuomilehto J, Todd J A, Clayton D G
Abstract excerpt
We have previously shown that the selection of haplotype tag single nucleotide polymorphisms (htSNPs) and their statistical analysis in a multi-locus transmission/disequilibrium test (TDT) results in a more cost-effective genotyping strategy in disease association studies of genes by minimising r...
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