Article
Role for dipeptidyl peptidase IV in tumor suppression of human non small cell lung carcinoma cells.
International journal of cancer - 10 May 2004
Wesley Umadevi V, Tiwari Shakuntala, Houghton Alan N
Abstract excerpt
Lung cancer is the leading cause of cancer death. Lung cancers produce a variety of mitogenic growth factors that stimulate tumor cell proliferation and migration. The cell surface protease, dipeptidyl peptidase IV (DPPIV), is involved in diverse biologic functions, including peptide-mediated cellular growth and differentiation. DPPIV is expressed in various normal tissues, including lung tissue, and its...
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