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Article

Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast.

Cell - 6 Feb 2004

Halme Adrian, Bumgarner Stacie, Styles Cora, Fink Gerald R

Abstract excerpt

The FLO gene family of Saccharomyces cerevisiae includes an expressed gene, FLO11, and a set of silent, telomere-adjacent FLO genes. This gene family encodes cell-wall glycoproteins that regulate cell-cell and cell-surface adhesion. Epigenetic silencing of FLO11 regulates a key developmental switch: when FLO11 is expressed, diploid cells form pseudohyphal filaments; when FLO11 is silent, the cells grow in yeast...

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Identifiers

PMID: 15016375
DOI: 10.1016/s0092-8674(04)00118-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast.PMID 15016375Read ↗

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