Founder mutations among the Dutch.

doi:10.1038/sj.ejhg.5201151

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Founder mutations among the Dutch.

European journal of human genetics : EJHG - 1 Jul 2004

Zeegers Maurice P A, van Poppel Frans, Vlietinck Robert, Spruijt Liesbeth, Ostrer Harry

Abstract excerpt

Many genetic disorders demonstrate mutations that can be traced to a founder, sometimes a person who can be identified. These founder mutations have generated considerable interest, because they facilitate studies of prevalence and penetrance and can be used to quantify the degree of homogeneity within a population. This paper reports on founder mutations among the Dutch and relates their occurrence to the...

Topics

Alleles
Female
Founder Effect
Gene Frequency
Genetic Diseases, Inborn
Genetics, Population
History, 15th Century
History, 16th Century
History, 17th Century
History, 18th Century
History, 19th Century
History, 20th Century
History, 21st Century
History, Ancient
History, Medieval
Humans
Male
Mutation

Source

Open in PubMed

Identifiers

PMID: 15010701
DOI: 10.1038/sj.ejhg.5201151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics