Article
Regression of a large goiter in a patient with resistance to thyroid hormone by every other day treatment with triiodothyronine.
Thyroid : official journal of the American Thyroid Association - 1 Jan 2004
Anselmo João, Refetoff Samuel
Abstract excerpt
Resistance to thyroid hormone (RTH) is a syndrome of reduced responsiveness to thyroid hormone caused, in the majority of cases, by mutation in the thyroid hormone receptor (TR) beta gene. Partial compensation through increase synthesis and secretion of thyroid hormone is mediated through TSH and results in thyroid gland enlargement. Goiters are of variable size but are recalcitrant to surgical treatment, and...
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