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Article

Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation

29 Jan 2004

Abstract excerpt

BACKGROUND: It is known that repeated failure of assisted reproduction treatment (ART) can be due to a paternal effect. This study was undertaken to analyse the possible relationship between ART failure and sperm DNA fragmentation. METHODS: Zygote morphology and the percentage of spermatozoa with fragmented DNA (assessed by TUNEL) were compared in two groups using donor oocytes for ICSI attempts. The experimental...

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Identifiers

PMID: 14998960
DOI: 10.1093/humrep/deh127

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