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Article

Bone morphogenetic protein receptor-II mutation Arg491Trp causes malignant phenotype of familial primary pulmonary hypertension.

Biochemical and biophysical research communications - 19 Mar 2004

Zhicheng Jing, Lihe Lu, Zhiyan Han, Xiansheng Cheng, Yubao Zou, Yuejin Yang, Rutai Hui

Abstract excerpt

A four-generation pedigree of familial primary pulmonary hypertension (FPPH) with 14 alive members was collected. In the family, three of the 14 alive familial members were diagnosed as FPPH. Mutations in bone morphogenetic protein receptor-II (BMPR-II) gene were screened by using sequencing anal...

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Share to Amino Acid Substitution
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Serine-Threonine Kinases

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Source

Identifiers

PMID: 14985116
DOI: 10.1016/j.bbrc.2004.01.158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14985116-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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