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A 38-Kilobase Pathogenicity Island Specific forMycobacterium aviumsubsp.paratuberculosisEncodes Cell Surface Proteins Expressed in the Host

21 Feb 2004

Abstract excerpt

We have used representational difference analysis to identify a novel Mycobacterium avium subsp. paratuberculosis-specific ABC transporter operon (mpt), which comprises six open reading frames designated mptA to -F and is immediately preceded by two putative Fur boxes. Functional genomics revealed that the mpt operon is flanked on one end by a fep cluster encoding proteins involved in the uptake of Fe(3+) and on...

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PMID: 14977927
DOI: 10.1128/iai.72.3.1265-1274.2004

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