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Article

Genetic analysis of mitochondrial complex II subunits SDHD, SDHB and SDHC in paraganglioma and phaeochromocytoma susceptibility.

Clinical endocrinology - 1 Dec 2003

Astuti Dewi, Hart-Holden Niki, Latif Farida, Lalloo Fiona, Black Graeme C, Lim Caron, Moran Anthony, Grossman Ashley B, Hodgson Shirley V, Freemont Anthony, Ramsden Richard, Eng Charis, Evans D Gareth R, Maher Eamonn R

Abstract excerpt

BACKGROUND: Germline mutations in three subunits of mitochondrial complex II (SDHB, SDHC and SDHD) may be associated with susceptibility to phaeochromocytoma (PC) and/or head and neck paraganglioma (HNPGL). METHODS: To further define the role of SDH subunit mutations in these disorders, we analysed a series of 22 probands with PC and evidence of genetic susceptibility (seven with familial PC only, one with...

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Source

Identifiers

PMID: 14974914
DOI: 10.1046/j.1365-2265.2003.01914.x

Genes

SDHD
SDHB
SDHC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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