Article
Prothrombin Shanghai: hypoprothrombinaemia caused by substitution of Gla29 by Gly.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jan 2004
Wang W, Fu Q, Zhou R, Wu W, Ding Q, Hu Y, Wang X, Wang H, Wang Z
Abstract excerpt
Prothrombin deficiency is a rare bleeding disorder inherited as an autosomal recessive trait. In this study, we reported a Chinese family with hereditary prothrombin deficiency. The proposita had a prolonged activated partial thromboplastin time (APTT, 71.6 s) and prothrombin time (PT, 28.0 s). The coagulation factors activities were normal except that prothrombin coagulation activity was markedly reduced, and...
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