Article
Meningiomas may be a component tumor of multiple endocrine neoplasia type 1.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2004
Asgharian Behnam, Chen Yuan-Jia, Patronas Nicholas J, Peghini Paolo L, Reynolds James C, Vortmeyer Alexander, Zhuang Zhengping, Venzon David J, Gibril Fathia, Jensen Robert T
Abstract excerpt
PURPOSE: Recently, an increased incidence of some nonendocrine tumors are reported in patients with multiple endocrine neoplasia type 1 (MEN 1). There are rare reports of meningiomas and other central nervous system tumors in these patients, but it is unknown if they are more frequent or if allelic loss of the MEN1 gene is important in their pathogenesis. The aim of this study was to address these two latter...
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