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Article

Female twin with hunter disease due to nonrandom inactivation of the X‐chromosome: A consequence of twinning

1 Dec 1992

Abstract excerpt

We report the occurrence of Hunter disease (mucopolysaccharidosis type II) in a karyotypically normal girl who was one of identical twins. Molecular studies showed nonrandom X-inactivation in both her fibroblasts and lymphocytes, while her normal twin showed equal usage of both X chromosomes. In view of previous reports of 7 pairs of identical female twins in which one had Duchenne muscular dystrophy, it seems...

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Identifiers

PMID: 1481858
DOI: 10.1002/ajmg.1320440625

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Female twin with hunter disease due to nonrandom inactivation of the X‐chromosome: A consequence of twinningPMID 1481858Read ↗

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