Article
[Mutation and amplification of RIT1 gene in hepatocellular carcinoma].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2004
Li Jin-tian, Liu Wei, Kuang Zhi-he, Zhang Ru-hua, Chen Han-kui, Feng Qi-sheng
Abstract excerpt
OBJECTIVE: To explore the mutation and amplification of RIT1 gene and their correlation with carcinogenesis of hepatocellular carcinoma (HCC). METHODS: The polymerase chain reactioindirect sequencing method was used for detecting the mutations in the sequence of all 6 exons in the RIT1 gene of 50 HCC tissues and paratumor tissues. And the amplification of RIT1 gene was examined by fluorescence quantitative...
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