Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosomal imbalances detected by comparative genomic hybridisation in atypical teratoid/rhabdoid tumours.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Apr 2004

Rickert Christian H, Paulus Werner

Abstract excerpt

INTRODUCTION: Atypical teratoid/rhabdoid tumours (AT/RT) are highly malignant embryonal tumours of the brain composed of rhabdoid cells. Inactivating mutations of the hSNF5/INI-1 gene located in the chromosomal region 22q11.2 are regarded as a crucial step in their molecular pathogenesis. Apart from monosomy or deletions of chromosome 22 not much data exists on additional chromosomal aberrations. METHODS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Aberrations

Share to Chromosomes, Human, Pair 22

Share to Infant, Newborn

Share to Nucleic Acid Hybridization

Share to Rhabdoid Tumor

Share to SMARCB1 Protein

Source

Identifiers

PMID: 14767597
DOI: 10.1007/s00381-003-0909-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosomal imbalances detected by comparative genomic hybridisation in atypical teratoid/rhabdoid tumours.PMID 14767597Read ↗

Chromosome 22q Deletions in Atypical Teratoid/Rhabdoid Tumors in AdultsSemantic proximity Read ↗

Description of a new oncogenic mechanism for atypical teratoid rhabdoid tumors in patients with ring chromosome 22.Semantic proximity Read ↗

A complex karyotype in an atypical teratoid/rhabdoid tumor: case report and review of the literature.Semantic proximity Read ↗

Atypical teratoid/rhabdoid tumor: short clinical description and insight into possible mechanism of the disease.Semantic proximity Read ↗

Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System: Report on WorkshopSemantic proximity Read ↗

High-resolution genomic analysis suggests the absence of recurrent genomic alterations other than SMARCB1 aberrations in atypical teratoid/rhabdoid tumors.Semantic proximity Read ↗

Atypical teratoid/rhabdoid tumors—current concepts, advances in biology, and potential future therapiesSemantic proximity Read ↗

Cyclin D1 is overexpressed in atypical teratoid/rhabdoid tumor with hSNF5/INI1 gene inactivation.Semantic proximity Read ↗

Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: An Intergroup Rhabdomyosarcoma StudySemantic proximity Read ↗

Monosomy 22 in rhabdoid or atypical tumors of the brainSemantic proximity Read ↗

Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors.Semantic proximity Read ↗

Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.