Article
The hormonal phenotype of Nonclassic 3 beta-hydroxysteroid dehydrogenase (HSD3B) deficiency in hyperandrogenic females is associated with insulin-resistant polycystic ovary syndrome and is not a variant of inherited HSD3B2 deficiency.
The Journal of clinical endocrinology and metabolism - 1 Feb 2004
Carbunaru Goldy, Prasad Pallavi, Scoccia Bert, Shea Patrick, Hopwood Nancy, Ziai Fuad, Chang Ying Tai, Myers Susan E, Mason J Ian, Pang Songya
Abstract excerpt
To test our hypothesis that the hormonal phenotype of mild 3beta-hydroxysteroid dehydrogenase (HSD3B) deficiency in hyperandrogenic females (HF) is related to insulin-resistant polycystic ovary syndrome (PCOS), we compared insulin sensitivity and gonadotropin secretion in HF with compromised ( do...
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