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Article

Systematic variation in osteoblast adhesion and phenotype with substratum surface characteristics.

Journal of biomedical materials research. Part A - 1 Mar 2004

Lim Jung Yul, Liu Xiaomei, Vogler Erwin A, Donahue Henry J

Abstract excerpt

Time-varying interactions of human fetal osteoblastic cells (hFOB 1.19) with materials of diverse chemical composition and surface energy, including biodegradable lactide/glycolide-based polymers, were assessed using a combination of assays sensitive to different phases of cell-substratum compatibility. Short-term (minutes to hours) cell-attachment-rate assays were used to measure the earliest stages of...

Topics

Alkaline Phosphatase
Biocompatible Materials
Biodegradation, Environmental
Cell Adhesion
Cell Differentiation
Cell Division
Cell Line
Humans
Materials Testing
Osteoblasts
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polyesters

Polyglycolic Acid

Structure-Activity Relationship

Surface Properties

Source

Identifiers

PMID: 14762930
DOI: 10.1002/jbm.a.20087

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