Article
A regulatory domain in the C-terminal extension of the yeast glycerol channel Fps1p.
The Journal of biological chemistry - 9 Apr 2004
Hedfalk Kristina, Bill Roslyn M, Mullins Jonathan G L, Karlgren Sara, Filipsson Caroline, Bergstrom Johanna, Tamás Markus J, Rydström Jan, Hohmann Stefan
Abstract excerpt
The Saccharomyces cerevisiae gene FPS1 encodes an aquaglyceroporin of the major intrinsic protein (MIP) family. The main function of Fps1p seems to be the efflux of glycerol in the adaptation of the yeast cell to lower external osmolarity. Fps1p is an atypical member of the family, because the protein is much larger (669 amino acids) than most MIPs due to long hydrophilic extensions in both termini. We have shown...
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