Article
Concentration of hydroxyproline in blood: a biological marker in occupational exposure to asbestos and its relationship with Pi*Z and Pi*S polymorphism in the alpha-1 antitrypsin gene.
American journal of industrial medicine - 1 Feb 2004
Mas S, Casterad X, Laso N, Lafuente M J, Panades R, Calleja A, Hernandez S, Turuguet D, Deulofeu R, Ballesta A, Ascaso C, Lafuente A
Abstract excerpt
BACKGROUND: Hydroxyproline (OHP) is one of the most abundant amino acids in collagen and, in general, it provides a good measure of overall collagen catabolism. METHODS: Asbestos workers suffering from asbestosis (cases n = 85); asbestos exposed workers without asbestosis (exposed controls, EC, n = 86), and non-exposed population (non-exposed controls, NEC, n = 122) were studied. The concentration of free OHP in...
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